Monday, October 5, 2009

Inositol Improves Ovulation and Hormone Balance in PCOS Women
We have more very good news about inositol, a member of the B-vitamin family.
Two recent studies confirm earlier studies that inositol improves hormone balance and helps to restore normal cycles in women who have polycystic ovarian syndrome.

In the most recent study, from the University of Modena and Reggio Emilia in Italy, 25 overweight PCOS women were given 2 grams of inositol daily for 12 weeks. Menstrual cycles were restored in all women who did not have a normal cycle. Insulin resistance, a primary cause of polycystic ovary syndrome, was reduced.

The authors of the study conclude: "Myo-inositol administration improves reproductive axis functioning in PCOS patients, reducing the hyperinsulinemic state that affects LH secretion."

The other study is from the University of Perugia in Italy. It is a randomized, double blind, placebo-controlled clinical trial, which medical authorities say is the "gold standard" of medical studies.

The researchers divided 92 PCOS women into two groups. One group was given a placebo, while the other group received 4 grams of inositol daily.
Compared to the placebo group, the inositol group had a shorter time to first ovulation, and had a higher frequency of ovulation. The effect on ovarian follicles appeared to be rapid, starting in the first week of treatment.
In addition, the inositol group lost weight while the placebo group gained weight.

The researchers conclude: "These data support a beneficial effect of myo-inositol in women with oligomenorrhea and polycystic ovaries in improving ovarian function."

These and other medical studies suggest that therapeutic doses of inositol would be beneficial for ovulation, reduction of insulin resistance and luteinizing hormone, and possibly for weight loss.

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